Project researcher/Doctoral researcher to study immunoregulation in autoimmunity and cancer in Molecular Systems Immunology Group at Turku Bioscience Centre, Finland

Disorders in immune system and lymphocyte function lead to immune diseases or cancer.  We aim at studying the molecular mechanisms underlying immune mediated diseases aiming at enabling individualized treatment in the future.

Projects

Molecular Systems Immunology group aims at understanding the regulation of human immune system to predict, prevent and treat immune mediated disorders. We study epigenetic and transcriptional regulation of T cells and molecular mechanisms of immune mediated diseases such as Type 1 Diabetes.

Project 1. is focused on studying how the novel long noncoding RNAs we have identified influence human T cell differentiation and their role in autoimmune diseases and cancer (Andrabi et al. Proc Natl Acad Sci U S A. 121:e2315363121, 2024 PMID: 38805281, Khan et al. Front. Immunol., 13: 856762, 2022 PMID: 35784351 and unpublished results).

Project 2. in collaboration with Orion Pharma Immuno-Oncology team studies molecular basis of human T cell exhaustion in cancer (Brunell et al. Front Immunol 14:1151632, 2023 PMID: 37122741 and unpublished results). A range of methods including single-cell genomics, mass cytometry, proteomics and CRISPR-Cas9 will be used in experimental work along with computational tools to address the questions. 


 

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Who we are looking for

  • Master’s degree in immunology, life sciences, biomedicine or other relevant field
  • High level of motivation, self-initiative and independency
  • Excellent team work and communication skills
  • Excellent language skills in English (both oral and written)
  • First-rate immunology and epigenetics knowledge and skills with a strong background in molecular and cell biology.
  • Publication record in international journals in at least in one of the following areas: immunology, molecular and cellular biology, autoimmunity, genetics

The salary is determined by the collective agreement system of the Finnish universities. These positions belong to our research personnel and the salary will be  2440 – 2800 eur/month in average.The position starts on Oct 1st, 2024 (or as agreed). The project researcher position is initially for two years. For a doctoral researcher 1-2 optional years are possible. There is a trial period of six months.

Please include a CV, full publication list, list of selected publications and contact information for three references in your application.

For further information please contact: Prof. Riitta Lahesmaa, e-mail: riitta.lahesmaa (at)utu.fi .

Enquiries on the application procedure may be directed to HR Specialist Paula Luoma paula.luoma(at)utu.fi

During 87.2024 - 31.7.2024 the application enquiries will be answered by our central HR services at hr-tuki(at)utu.fi.

 

Benefits

  • A dynamic, international work environment
  • Access to state-of-the-art facilities and resources
  • Flexible work hours and Nordic-style work-life balance
  • Support for continuous professional development
  • Collaborative and inclusive work culture

Description of our organizations

Turku Bioscience Centre is a joint research institute of University of Turku and Åbo Akademi University. The mission of the Centre is to promote high quality research and training. The Centre has excellent state-of-the-art technology platforms and expertise in single-cell omics, NGS, epigenomics, proteomics, computational biology and high-end cell imaging and cytometry.

Orion Immuno-Oncology (IO) Team led is by Dr. Anil Thotakura.  IO team is accountable for innovative drug discovery projects, identification of clinical unmet need, identification & experimental validation of potential IO drug targets within state-of-the-art laboratories and technologies.

Turku Bioscience Centre

Turku Bioscience is an advanced core facility and research centre hosted jointly by University of Turku and Åbo Akademi University. Our aim is to provide complete packages of service expertise and know-how to provide both academic and corporate research groups the tools and means to shorten the runway from an initial discovery to the take-off of a success story. To this end, we aim to stay at the frontiers of new technologies and research and we are also actively facilitating interactions and joint projects between academia and industry.

The University of Turku is an inspiring and international academic community of 25,000 students and staff in Southwest Finland. We build a sustainable future with multidisciplinary research, education, and collaboration. With us, your work will have a significant impact and relevance in the changing world.

See our open vacancies

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Project researcher/Doctoral researcher to study immunoregulation in autoimmunity and cancer in Molecular Systems Immunology Group at Turku Bioscience Centre, Finland

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